Dear Nony,
The University of California (Irvine) published a study about a year or so ago, in which they treated mice with Alzheimer's with niacinamide (Vitamin B3) for 4 months. Afterwards, the treated mice had the same memory function as healthy mice, in effect they were cured. They are now in the midst of a human clinical trial. It will be interesting to see the results when the test is concluded and if the same (or significant) improvement is seen in humans.
The doses given to the mice were the equivalent of 2-3 grams of B3 and in the human trial they are using 2 doses of 1500mg per day. (I've seen others recommend that this dosage be split further. Personally, just 100mg causes uncomfortable "flushing" and even swelling for me (this lasts about an hour or two), so that may be a bit of a deterrent for some people (other people may not have the same reaction and this could be a non-issue). I haven't taken B3 on a regular basis to know if the body adapts to this and the side-effects become less noticeable over time. Although, if the study results show significant improvement, then that may be a trade-off worth making.
